PARTIAL P53 REACTIVATION IS SUFFICIENT TO INDUCE CANCER REGRESSION

Partial p53 reactivation is sufficient to induce cancer regression

Abstract Background Impaired p53 function is one of the central molecular features of a tumor cell and even a partial reduction in p53 activity can increase the cancer risk in mice and men.From a therapeutic perspective it is noteworthy that tumor cells often become addicted to the absence of p53 providing a rationale for developing p53 reactivatin

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Does the short-term learning effect impact vertical jump performance assessment on a portable force plate system?

One of the reoccurring questions that arises during the countermovement vertical jump (CVJ) assessment is whether the learning effect has an impact on the accuracy of the results obtained.Thus, the purpose of the present investigation was to examine the impact of the short-term learning effect on the assessment of lower-body neuromuscular performan

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Solitary Rectal Ulcer Syndrome: A Biopsychosocial Assessment

Background: Solitary rectal ulcer syndrome (SRUS) is a chronic disorder of the gastrointestinal tract and its etiology is not well understood.There is no specific treatment for this syndrome and patients with SRUS may, for years, experience many complications.The aim of the present research was the biopsychosocial study of patients with SRUS.Method

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